It has been well-known that topological phenomena with fractional excitations, i.e., the fractional quantum Hall effect (FQHE) will emerge when electrons move in Landau levels. In this talk, I will show FQHE can emergy even in the absence of Landau levels in interacting fermion models and boson models. The non-interacting part of our Hamiltonian contains topologically nontrivial flat band.